Skip to main content

What Does AAQI Do With the Money?

If you have ever wondered where the money the Alzheimers' Art Quilt Initiative is spent, read on!  I am attaching information here I have just received from AAQI.  You can read this and more on the site!


The Alzheimer’s Art Quilt Initiative (AAQI) has awarded its ninth grant to Dr. Chris B. Schaffer, Professor in the Department of Biomedical Engineering at Cornell University. The $30,000 grant is the second grant the charity has awarded for Alzheimer’s research at Cornell University.


Dr. Schaffer explains his work: “In the conventional view of Alzheimer’s disease it is thought that neurons in the brain are damaged by the accumulation of a small protein called amyloid-beta, but recent work shows that the blood vessels in the brain are also affected by amyloid-beta. In addition, Alzheimer patients have less blood flow in their brains than people without the disease. It is possible that the vascular effects of amyloid-beta and this blood flow decrease could contribute to the symptoms of Alzheimer’s disease and add to the impact of the direct neuronal damage by amyloid-beta.

Our work suggests that the blood flow decrease may be caused by white blood cells that block small blood vessels in the brain. Normally, white blood cells become activated, stick to the wall of blood vessels, then exit the vasculature and tissue in response to an infection or injury. However, in Alzheimer’s disease such activation may be detrimental because it could slow blood flow and deprive brain cells of oxygen and nutrients. In addition, the decreased blood flow may trigger the accumulation of more amyloid-beta, producing a vicious cycle of injury to the brain.

In this work, we will test potential therapies that prevent the white blood cells from plugging blood vessels. We expect to see an increase in blood flow and hope to see a decrease in amyloid-beta accumulation. This work relies on new imaging techniques that enable us to track changes in amyloid-beta and blood flow with micrometer resolution in mice that are engineered to develop Alzheimer’s disease. If successful, this therapy could potentially slow the progression of Alzheimer’s disease in patients.”
Learn more about research that has been funded by the AAQI here:

http://www.alzquilts.org/researchawards.html

Comments

Post a Comment

Popular posts from this blog

Giveaway Day! (CLOSED)

I am very happy to be joining in the Giveaway Day through Sew, Momma, Sew .  I have chosen to share one of my finds from a shopping trip, or treasure hunts as I think of them.  This is an antique sewing box -  I could not resist it when I saw it for sale!  Were you able to guess the item from the sneak peek earlier in the week? The box itself is fairly small, 8 inchs X 6 inchs and 4 inches high (20 cm X 15 cm and 10 cm high).  From my research it is of Asian origin. Inside the sewing box is lined with hand-painted silk.  The inside of the lid features a neat little needlebook. In the bottom of the sewing box there are more beautiful hand-painted blossoms and an attached pincushion.  I hope you are as charmed by this little box as I was when I found it and that you will enter my giveaway.  I will be pleased to mail internationally so everyone is invited to enter. To enter, visit my Etsy shop and then come back and leave me a...
119 comments
Read more

BAS - Week 73 - Raised Fishbone Leaves (and Tutorial)

It took me a little while to get this one ready - lots of photos in the tutorial.  This Build a Seam (BAS) Challenge is for Raised Fishbone Stitch leaves.  With a little practice you will get much better results than I did - this was my first attempt on these as well.  For some reason I have basically avoided fishbone stitch but no time like the present to learn!  I hope you enjoy this BAS Challenge! Begin by marking your leaves on your fabric.  You will find it handy to have an outline to follow while stitching.  I used a mechanical pencil to lightly mark mine - hopefully not so lightly you can`t see them! To begin, bring your needle up at the point of the leaf and take it down again about halfway down on the center vein. Now come up again directly to the left of that, on the outside edge of the leaf. Take your needle down again just barely to the right and down from the top leaf point. And bring it up again just barely to the left and down of the point...
4 comments
Read more

Giveaway!

I am feeling like celebrating for various reasons! Firstly, this is my 100th post on my blog and that seems worthy of a little celebration. Secondly, I can now count the days on this year's camping season on my fingers! It has been a busy summer out here at the campground and I am anticipating getting home for a rest - I am so looking forward to hot showers, a real bed, good lighting and my comfy stitching chair! So, I have decided to celebrate with a giveaway! I think these are great fun and have put my name down for several and even won once so it feels like time to be on the hosting end for a change. I have decided to give away a squishie of items for stitching, embellishing and inspiration. I can't show you a picture right now because of the twist I have come up with! I'll start out with a squishie containing some fun items like an oya or two, specialty threads and fancy yarns, a silkie and a couple other things. For every person who puts their name in the draw by leavi...
42 comments
Read more